Supply, Delivery and Commissioning of a large scale oligonucleotide synthesis and purification platform

Descriptions

The Department of Pure & Applied Chemistry at the University of Strathclyde, are looking to understand if the market can provide large scale oligonucleotide synthesis equipment. The equipment is requried to provide the following: - The offered solution can provide automated large scale oligonucleotide synthesis - The offered solution will provide capability for downstream purification - The offered solution provides capability for multiple amidite bottles to support synthesis - Can accommodate oligonucleotide synthesis on a variety of scales (1 mmol and above) - Can provide a computer control and software system that drives the automated synthesiser - The offered solution must be capable of inerting all reagent bottles - The offered system must have the ability to provide UV and conductivity monitoring in the synthesis platform - The offered system must be able to support a range of columns in the synthesis platform - The offered solution for downstream chromatography must have automated fraction collection and control software - The offered solution for downstream chromatography must have UV monitoring using at least two wavelengths - The offered solution for downstream chromatography must be capable of providing a flow rate of up to 150 mL/min - The offered solution for both synthesis and purification must include at least 24 months warranty, including 1 planned maintenance visit - Full training must be provided by the supplier on the platform supplied It is encouraged that suppliers interested in this opportunity complete the questionnaire attached. Please note this questionnaire is non-committal and purely for information purposes. Please complete the questionnaire by 8th March 2024 and return to jemma.wylie@strath.ac.uk