High-Throughput Sequencing Services

Descriptions

The primary aim of this procurement is to secure a high-throughput sequencing service provider to perform sequencing services for the Cell and Gene Therapy (CGT) Catapult on a fee-per-service basis. This service will support the CGT Catapult's mission of accelerating the commercialization of innovation from research and overcoming technical barriers in advanced therapy medicinal product (ATMP) development. The selected provider's services will complement CGT Catapult's unique technical facilities and expertise at its London site.

This procurement seeks comprehensive high-throughput sequencing services. These services will be utilized for deep process characterization, particularly for processes like stem cell differentiation and viral vector manufacturing. The required services include, but are not limited to:

Lot 1 - High-throughput short-read sequencing of libraries generated by CGT Catapult (i.e., sequencing only)

Lot 2 - Bulk RNA sequencing

Lot 3 - Bulk small RNA sequencing

Lot 4 - Single-cell RNA sequencing (scRNA-seq) of cryopreserved/fixed samples

Lot 5 - AAV genome short-read sequencing

Lot 6 - Sanger sequencing