Awarded
Mass Cytometer.
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Descriptions
The Francis Crick Institute requires a high-end Mass Cytometer that incorporates the very latest technologies available in the field, to overcome the limitations posed by traditional flow cytometry (limited number of analytes and ability to resolve tagged antibodies with overlapping fluorophores). Mass cytometry is a relatively new technology that overcomes these limitations by using lanthanide-labeled antibodies to tag cells that are then measured using a mass ctytometer (also termed CyTOF). The outcome is an improved signal-to-noise ratio and little overlap of signal, enabling cells to be labeled with far greater numbers of different antibodies than conventional flow cytometry, with over 100 detection channels being feasible. The resulting multiparametric data then allows researchers to identify not only complex protein marker combinations but also pathway activation states in normal and diseased biological systems.
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CPV Codes
38434000 - Analysers
38400000 - Instruments for checking physical characteristics
38434510 - Cytometers
38430000 - Detection and analysis apparatus
Keywords
fluid analysers
cytometers
lab analyzers
analysers
hardness testers
flow cytometers
chemical analysers
process analysers
cell analysis systems
dimensional testers
texture analyzers
calibration gauges
component analysers
physical property gauges
lab cell counters
cell sorting cytometers
fluorescence cytometers
measuring devices
lab analysis devices
surface measurement instruments
analytical detection systems
immunophenotyping cytometers
sample investigation tools
sensor-based detection tools
detection and analysis apparatus
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